DNA · Bioelectronics · Biooptics

Molecular systems that write, store & compute information.

DNA and molecular hardware — electric-field synthesis, DNA data storage, molecular computing, and genetic diagnostics — for memory and biotechnology beyond the limits of CMOS.

PI Youngjun Song, Ph.D. · Incheon National University

636
Citations
15
h-index
5
Research thrusts
2026
Latest in Science Adv.
Research

Five thrusts, one idea — DNA as an information medium.

From custom genes on a chip, to archives in DNA, to disease readout from a drop of blood — a single molecular toolkit, five directions.

01

DNA Synthesis & Synthetic Biology

On-demand DNA, gene, and mRNA writing

Direct electric-field DNA writing on microelectrode chips (EPCR), plus assembly of genes, plasmids, and mRNA — an on-chip, IDT-style foundry for programmable synthetic biology.

EPCRssDNAmRNA/IVTFoundry
02

DNA Data Storage

Archives that fit in a drop of liquid

High-density encoding of digital data — 3D models, point clouds, cultural heritage — into DNA, with fast decoding via tailored error-correcting codecs and a liquid, electrically random-accessed DNA drive.

CODECData-InkRandom-AccessHeritage
03

Molecular & DNA Computing

Logic and memory made of molecules

Computation with molecules — droplet-based Boolean logic, in-cell miRNA logic driving fluorescent-protein outputs, multi-bit FRET molecular memory, and machine-learning-assisted strand-displacement circuits.

BooleanFRETStrand-DispIn-Cell
04

Genetic Diagnosis & Therapy

Disease readout from nucleic acids

Detection of disease-linked microRNA and cell-free DNA via enzyme-free chemical ligation and electric/optical chips — liquid biopsy coupled with AI for early diagnosis, plus emerging XNA/ASO therapeutic directions.

miRNALiquid-BiopsyDEPAI-Dx
05

Enabling Platforms

AI, automation & devices that power the lab

Cross-cutting infrastructure — AI for science, self-built lab robotics in place of costly instruments, and the nanomaterials and semiconductor devices beneath every project: CNT composites, liquid-metal microfluidics, memory arrays.

AI4ScienceAutomationCNTLiquid-Metal
Technology · Foundry

An on-chip DNA & gene foundry

Electric-field synthesis (EPCR) — direct DNA and gene writing on microelectrode chips. A programmable, IDT-style foundry for custom oligos, genes, and mRNA, with industrial translation through our spin-off STD BioElec.

EPCR · STD BioElec

Write once, reuse ×10⁵.

  • Electric-field DNA / gene synthesis on reusable chips (>10⁵ cycles)
  • Custom oligos, gBlock-style genes, plasmid & mRNA/IVT assembly
  • Cell-free protein expression pipelines
  • Commercial translation via STD BioElec bio-foundry

5′—ATCG GATE ACGT CODE TCGA—3′

Selected Publications

Recent work

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